Transferrin Receptor CD71 Implicated in Celiac Disease

Transferrin Receptor CD71 Implicated in Celiac Disease

Celiac.com 03/26/2008 - On peculiarities of celiac disease is that not all gliadin proteins (peptides) are equal in terms of creating an adverse immune response. Certain peptides are completely broken down during intestinal transport, notably those that are the same size or larger than peptide 57-68. Other peptides, like the peptides 31-49 (P31-41), and the 3-mer gliadin peptide, are transported across the intestinal barrier intact and end up provoking the adverse immune response that is characteristic of celiac disease.


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